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刘兆国

作者:金飞     日期:2021-10-26   点击数:60  

师资介绍


刘兆国,男,汉,198711月生,博士,副教授,硕士研究生导师


研究方向:

中药抗肿瘤药理、抗消化系统疾病药理


社会学术兼职:

江苏省中药药理委员会委员兼秘书

江苏省双创人才(科技副总)

Frontiers in Bioscience-Landmark杂志(IF:4.009)编委


基金项目

1. 国家自然科学基金面上项目,CMSS1/RBM34/DDX5复合体调控端粒酶新机制的发现及其在非小细胞肺癌(NSCLC)发生发展中的作用机制,2020/01-2023/1258万元,在研,参加;

2. 中国博士后科学基金面上项目,2018M642296,黄葵胶囊抗顺铂所致肾毒性的机理研究,2018/11-2020/085万元,在研,主持;

3. 南通市科技局项目,JC2021025,基于 MIF/MIOX/铁死亡信号调控探究黄葵胶囊抗顺铂急性肾损伤的机制研究,2021/07-2023/065万元,在研,主持;

4. 国家自然科学青年基金项目,81703884,基于PKCδ介导的自噬调控探究黄葵胶囊对顺铂肾毒性的保护作用及分子机制,2018/01-2020/1220万元,已结题,主持;

5. 江苏省高等学校自然科学研究面上项目,17KJB360012,黄葵胶囊对顺铂肾毒性的保护作用及机理研究,2017/09-2019/083万元,已结题,主持。


代表性论文:

1. Chang Chen#, Jingya Gu#, Jue Wang#, Yu Wu, Aihua yang, Tingting Chen, Tingting Zhou, Zhaoguo Liu*(通讯作者). Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis throughinflammation inhibition by regulating SIRT3-mediated NF-κB P65nuclear expression[J]. International Immunopharmacology, 2021, 90:107206. (IF:4.932,二区)

2. Jingya Gu#, Chang Chen#, Jue Wang#, Tingting Chen, Wenjuan Yao, Tingdong Yan*, Zhaoguo Liu*(通讯作者). Withaferin A Exerts Preventive Effect on Liver Fibrosis through Oxidative Stress Inhibition in a Sirtuin 3-Dependent Manner [J]. Oxidative Medicine and Cellular Longevity, 2020, 2020: 2452848. (IF:5.076,二区)

3. Yuqin Wang #, Chunling Li#, Jingya Gu #, Chang Chen, Jiaxin Duanmu, Jing Miao, Wenjuan Yao, Jinhua Tao, Mengjue Tu, Biao Xiong, Lingling Zhao*, Zhaoguo Liu*(通讯作者). Celastrol exerts anti-inflammatory effect in liver fibrosis via activation of AMPK-SIRT3 signaling [J]. Journal of Cellular and Molecular Medicine, 2020, 24(1): 941-953. (IF:4.658,二区)

4. Lin Zhang #, Chang Chen #, Jiaxin Duanmu, Yan Wu, Jinhua Tao, Aihua Yang, Xiaoqin Yin, Biao Xiong, Jingya Gu, Chunling Li, Zhaoguo Liu *(通讯作者). Cryptotanshinone inhibits the growth and invasion of colon cancer by suppressing inflammation and tumor angiogenesis through modulating MMP/TIMP system, PI3K/Akt/mTOR signaling and HIF-1α nuclear translocation[J]. International Immunopharmacology, 2018, 65: 429-437. (IF:4.932,二区)

5. Zhaoguo Liu#,*(通讯作者), Pingting Zhu#, Lin Zhang, Biao Xiong, Jinhua Tao, Wei Guan, Chunling Li, Chang Chen, Jingya Gu, Jiaxin Duanmu, Wei Zhang*. Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis[J]. Biomedicine & Pharmacotherapy, 2018, 103:1262-1271. (IF:4.545,三区)

6. Jinlin Zhang, Aihua Yang, Yu Wu, Wei Guan, Biao Xiong, Xiaoqing Peng, Xiaojin Wei, Chang Chen, Zhaoguo Liu* (通讯作者). Stachydrine ameliorates carbon tetrachloride-induced hepatic fibrosis by inhibiting inflammation, oxidative stress and regulating MMPs/TIMPs system in rats[J]. Biomedicine & Pharmacotherapy, 2018, 97:1586-1594.  (IF:4.545,三区)

7. Pingting Zhu#, Yu Wu#, Aihua Yang, Xingsheng Fu, Ming Mao, Zhaoguo Liu*(通讯作者). Catalpol suppressed proliferation, growth and invasion of CT26 colon cancer by inhibiting inflammation and tumor angiogenesis[J]. Biomed Pharmacother, 2017, 95:68-76. (IF:4.545,三区)


授权专利:

刘兆国,杨圣菊,彭晓露,陈畅,顾静雅. 白桦醇及其衍生物在制备抗肿瘤药物中的应用,专利号:ZL201910201989.5


所获奖项及荣誉:

南通大学青年教师讲课竞赛一等奖

南通大学优秀教育工作者