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陈婷婷

作者:金飞     日期:2021-10-26   点击数:46  

师资介绍


姓名:陈婷婷

性别:女

民族:汉

出生年月:198951

职称:副教授

学历:博士

职务:无

研究方向:神经药理


基金项目:

  1. 国家自然科学基金,青年基金,81901098,抑制Ras法尼基化改善阿尔兹海默病认知功能的分子机制研究,2020–012022–1220.50万,在研,主持。

  2. 江苏省自然科学基金,青年基金,BK20190923,抑制Ras 法尼基化抗痴呆的神经保护作用机制研究,2019–072022–620万,在研,主持。

  3. 南通市科学计划项目,JC2018009,小G 蛋白Ras 活性抑制对阿尔兹海默病认知功能的调控机制,2018–072020–06,5万,结题,主持

科研成果:

代表性论文

1Chen Tingting*; Cai Chengyun; Wang Lifeng; Li Shixin; Chen Ling *; Farnesyl Transferase Inhibitor Lonafarnib Enhances α7nAChR Expression Through Inhibiting DNA Methylation of CHRNA7 and Increases α7nAChR Membrane Trafficking, Frontiers in Pharmacology, 2020, 11.

2Chen Tingting#; Wang Ya#; Zhang Tingting; Zhang Baofeng; Chen Lei; Zhao Liandong; Chen Ling*; Simvastatin Enhances Activity and Trafficking of α7 Nicotinic Acetylcholine Receptor in Hippocampal Neurons Through PKC and CaMKII Signaling Pathways, Frontiers in Pharmacology, 2018, 9: 362.

3Chen Tingting; Tanaka Motoki; Wang Ya; Sha Sha; Furuya Kishio; Chen Ling*; Sokabe M*; Neurosteroid dehydroepiandrosterone enhances activity and trafficking of astrocytic GLT-1 via σ1 receptor-mediated PKC activation in the hippocampal dentate gyrus of rats, Glia, 2017, 65: 1491-1503.

4Chen Tingting; Wang Conghui; Sha Sha; Zhou Libin; Chen Lei*; Chen Ling*; Simvastatin Enhances Spatial Memory and Long-Term Potentiation in Hippocampal CA1 via Upregulation of α7Nicotinic Acetylcholine Receptor, Molecular Neurobiology, 2016, 53: 4060-4072.

5Chen Tingting; Zhang Baofeng; Li Guoxi; Chen Lei; Chen Ling*; Simvastatin enhances NMDA receptor GluN2B expression and phosphorylation of GluN2B and GluN2A through increased histone acetylation and Src signaling in hippocampal CA1 neurons, Neuropharmacology, 2016, 107: 411-421.