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范博义

作者:金飞     日期:2021-10-26   点击数:31  

师资介绍



姓名范博义

性别:男

民族:汉

出生年月:1989.01

职称:副教授

学历:博士

职务:无

研究方向:活性天然产物的开发利用

社会学术兼职:无

基金项目:

1.南通市科技项目,香樟叶中天然活性化合物的发现及其药理机制研究,2021.07-2023.063万,主持

2. 国家自然科学基金青年项目,基于自噬-溶酶体通路的土丁桂中潜在抗阿尔茨海默症树脂糖苷类成分的发现及其作用机制研究,2019.01-2021.12,26万,主持

3. 南通市科技项目,土丁桂中新颖抗AD活性成分及作用机制研究,2016.10-2018.093万,主持

科研成果:

  1. 范博义,赵文迪,陆云,杨敏。田旋花总树脂糖苷提取物及其制备方法和医学用途,专利号:ZL201810244054.0


代表性论文:

1. Kai-Nan Song, You-Jia Lu, Cheng-Jiao Chu, Yan-Ni Wu, Hui-Lian Huang, Bo-Yi Fan*, and Guang-Tong Chen*.Biotransformation of betulonic acid by the fungus Rhizopus arrhizus CGMCC 3.868 and antineuroinflammatory activity of the biotransformation products. Journal of Natural Products 2021, DOI: 10.1021/acs.jnatprod.1c00480

2. Bo-Yi Fan, Yun Lu, Min Yang, Jian-Lin Li*, Guang-Tong Chen*. Evolvulins I and II, resin glycosides with a trihydroxy aglycone unit from Evolvulus alsinoides. Organic Letters 2019, 21(16), 6548–6551.

3. Bo-Yi Fan, Ye He, Yun Lu, Min Yang, Qing Zhu, Guang-Tong Chen*, Jian-Lin Li*.Glycosidic acids with unusual aglycone units from Convolvulus arvensis. Journal of Natural Products 2019, 82, 1593-1598.

4. Bo-Yi Fan, Bao-Cheng Jiang, Sen-Sen Yan, Bo-Hui Xu, Hui-Lian Huang, Guang-Tong Chen* Anti-inflammatory 18β-glycyrrhetinin acid derivatives produced by biocatalysis. Planta Medica2019, 85, 56-61.

5. Guang-Tong Chen, Yun Lu, Min Yang, Jian-Lin Li*, Bo-Yi Fan*. Medicinal uses, pharmacology, and phytochemistry of Convolvulaceae plants with central nervous system efficacies: a systematic review. Phytotherapy Research 2018, 32(5), 823-864.